ORDER SNAKE ANTIVENOM, SNAKE VENOM SERUM FROM THE MOST RELIABLE SOURCE, THE RED CROSS ORGANIZATION

How to produce snake antivenom serum


The official Red Cross snake farm is a world leader in producing various types of serum for snakebite victims in terms of quality and quantity, and is has been supplying for decades many types of snake antivenin to treat bites from snakes as cobra (Ophiophagus Hannah), king cobra (Ophiophagus Hannah Snake), banded krait (Bungarus fasciatus Snake), Russell's viper (Daboia Russelli Siamensis), Malayan pit viper (Calloselasma Rhodostoma), and Green Pit Viper (Trimeresurus Albolabris).

Antiserums are normally prepared from blood plasma from horse immunized by injection of antigen to let the horse’s immune system generate "Immunoglobulin" that has neutralization activity and antigen specificity.

For snake antivenin production the snake venom has to be injected into a horse because after injection the horse will generate immunoglobulin, then its blood will be collected and the hemoglobin will be separated from plasma. This plasma fraction containing the immunoglobulin is used for antivenom production.

The plasma consists of many proteins but only immunoglobulin can neutralize snake venom so useless proteins for venom serum production such as albumin, fibrinogen and others are removed to reduce allergic reaction when injected.


Clear explanation about how is snake antivenom produced by Red cross:

- First, snake venom is injected into a horse and the weekly dosage is gradually increased until the horse is able to produce its own natural antivenin. To ensure that the product has the required strength, blood is drawn from the horse and tested at intervals.

- Second, when the antivenin meets the required strength, some blood is drawn from the horse (without causing any harm to the animal) and preserved in a clean, safe container. Then the antivenin is purified thanks to sedimentation and sifting processes so that non-antibody-related proteins which tend to cause allergy when administered to patients are extracted from the compound that is the most efficient against snake venom.

- Third, the serum is bottled and dehydrated to make it easy to transport and store for long periods (up to 5 years).

Snake antivenin is now ready but to ensure the serum's effectiveness and safety many quality control tests are also conducted on animals under laboratory conditions in compliance with World Health Organization standards to be sure that Red cross antivenom is proper for human use and 100% safe for patients.

 

 

Red Cross Antivenom Production Process

 

 

 

 

 

 




Neuro Polyvalent Snake Antivenom for Cobra and King Cobra, Banded Krait, and Malayan Krait Venom

Neurotoxic Polyvalent Snake Antivenom by Red Cross and Red Crescent
Order Neurotoxic Polyvalent Snake Antivenin online Red Cross and Red CrescentOrder Neurotoxic Polyvalent Snake Antivenin online Red Cross and Red Crescent
139.00€

Neurotoxic Polyvalent Snake Antivenom for Cobra and King Cobra, Banded Krait, and Malayan Krait Venom

This Neuro Polyvalent Snake Antivenom can be used against Ophiophagus Hannah, Naja Kaouthia, Bungarus fasciatus venom and Bungarus candidus snakes venom.

 

 

 

 

 

 

 

 

 

 

Cobra Naja Kaouthia Antivenom Red Cross

Cobra Naja Kaouthia Antivenom Red Cross

Malayan Krait Bungarus Candidus Antivenom Red Cross

 

Malayan Krait Bungarus Candidus Antivenom Red Cross

Banded Krait Bungarus fasciatus Antivenom Red Cross

 

Banded Krait Bungarus fasciatus Antivenom Red Cross

 

The Red Cross produces 2 kinds of polyvalent snake antivenom, one hematotoxic polyvalent antivenom against hematotoxic snake venom (Malayan pit viper, Green pit viper and Russell’s viper snakes) and one Neurotoxic Polyvalent Snake Antivenom against neurotoxic snake venom (Cobra, King cobra, Banded Krait and Malayan Krait snakes).

 

Administration

The freeze-dried Neurotoxic Polyvalent Snake Antivenom must be reconstituted with the solution supplied (or 10 ml of sterile water for injection) prior to the administration.

 

Dosage of Neurotoxic Polyvalent Snake Antivenom to neutralize Cobra and King Cobra Venom, Banded Krait Venom, and Malayan Krait Venom

The initial dose of this Neurotoxic Polyvalent Snake Antivenom is 50 ml of reconstituted antivenin that should be given by slow intravenous infusion (approx. 2 ml/min) but the Cobra antivenin initial dose is 100 ml. Subsequent dose can be given every 12 hours according to the clinical symptoms.

Contra-indication

None, unless the patient is known to be hypersensitive to constitutions of the product, appropriate precautions must be taken.

Side effects

Occasionally, transient tenderness at the injection site, cutaneous reaction and alterations in temperature may occur. In some cases nausea, vomiting and also circulatory reactions (e.g. tachycardia, bradycardia, hypotension, sweating, vertigo) and allergic reactions (e.g. with flush, urticaria, dyspnea) have been observed, extending in isolated cases as far as shock. Therefore, the patient should be monitored for an extended period of time.Therapeutic measures depend on the nature and severity of side effects. Antihistamines, if necessary adrenaline, high doses of corticosteroids, volume replacement, oxygen.

Special precautions

In cases of Cobra, King Cobra and Krait bites, respiratory support may be essential. Since Neurotoxic Polyvalent Snake Antivenom antivenin is prepared from horse serum, sensitization to heterologous protein may occur in some individuals. To avoid serious allergic reactions, skin test should be performed prior to the administration by injection of 0.02 ml of 1:100 antivenin dilution intradermally. It should be noted that the skin test may not predict the anaphylaxis nor delay serum sickness reactions.

Storage and stability

Keep in tightly closed container and store below 25-degree Celsius. The product shall have a shelf life of 5 years from the manufacturing date.

The manufacturing plant of QSMI has developed to meet the GMP requirement and get the GMP certificated from FDA since 2003.

 

 

Free Worldwide 3 Days Delivery Express Shipping With Tracking Number and Insurance.

139.00€



Hemato Polyvalent Snake Antivenom for Asian Snakes as Malayan Pit Viper, Green Pit Viper, and Russell's Viper

Hematotoxic Polyvalent Snake Antivenom by Red Cross
Order Hematotoxic Polyvalent Snake Antivenin by Red CrossOrder Hematotoxic Polyvalent Snake Antivenin by Red Crescent
139.00€

Hematotoxic Polyvalent Snake Antivenom for Asian Snakes as Malayan Pit Viper, Green Pit Viper, and Russell's Viper

This Hemato Polyvalent antivenom can be used for Calloselasma rhodostoma, Trimeresurus albolabris and Daboia russelli siamensis snakes venom.

 

 

 

 

 

 

 

 

 

 

Green Pit Viper Trimeresurus Albolabris Antivenom Red Cross

Green Pit Viper Trimeresurus Albolabris Antivenom Red Cross

Malayan Pit Viper Calloselasma Rhodostoma Antivenom Red Cross

Malayan Pit Viper Calloselasma Rhodostoma Antivenom Red Cross

Russell’s Viper Daboia Russelli Siamensis Antivenom Red Cross

Russell’s Viper Daboia Russelli Siamensis Antivenom Red Cross

 

The Red Cross produces 2 kinds of polyvalent snake antivenom, one Hematotoxic Polyvalent Snake Antivenom against hematotoxic snake venom (Malayan pit viper, Green pit viper and Russell’s viper snakes) and one neurotoxic antivenom against neurotoxic snake venom (Cobra, King cobra, Banded Krait and Malayan Krait snakes).

 

Administration

The freeze-dried Hematotoxic Polyvalent Snake Antivenom must be reconstituted with the solution supplied (or 10 ml of sterile water for injection) prior to the administration.

 

Dosage of Hematotoxic Polyvalent Snake Antivenom to neutralize Malayan Pit Viper venom, Green Pit Viper venom, and Russell’s Viper venom

The initial dose of this hematotoxic polyvalent snake antivenom is 30 ml of reconstituted antivenin that should be given by slow intravenous infusion (approx. 2 ml/min). Subsequent dose can be given every 6 hours according to the clinical symptoms.

Contra-indication

None, unless the patient is known to be hypersensitive to constitutions of the product, appropriate precautions must be taken.

Side effects

Occasionally, transient tenderness at the injection site, cutaneous reaction and alterations in temperature may occur. In some cases nausea, vomiting and also circulatory reactions (e.g. tachycardia, bradycardia, hypotension, sweating, vertigo) and allergic reactions (e.g. with flush, urticaria, dyspnea) have been observed, extending in isolated cases as far as shock. Therefore, the patient should be monitored for an extended period of time.Therapeutic measures depend on the nature and severity of side effects. Antihistamines, if necessary adrenaline, high doses of corticosteroids, volume replacement, oxygen.

Special precautions

Since the Hematotoxic Polyvalent Snake Antivenom is prepared from horse serum, sensitization to heterologous protein may occur in some individuals. To avoid serious allergic reactions, skin test should be performed prior to the administration by injection of 0.02 ml of 1:100 antivenin dilution intradermally. It should be noted that the skin test may not predict the anaphylaxis nor delay serum sickness reactions.

Storage and stability

Keep in tightly closed container and store below 25-degree Celsius. The product shall have a shelf life of 5 years from the manufacturing date.

The manufacturing plant of QSMI has developed to meet the GMP requirement and get the GMP certificated from since 2003.

 

 

Free Worldwide 3 Days Delivery Express Shipping With Tracking Number and Insurance.

139.00€



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