Hematoxic Polyvalent Snake Antivenom for Asian Snakes as Malayan Pit Viper, Green Pit Viper, and Russell’s Viper.
This Hemato Polyvalent antivenom can be used for Calloselasma rhodostoma, Trimeresurus albolabris and Daboia russelli siamensis snakes venom.
 Green Pit Viper Trimeresurus Albolabris Antivenom Red Cross |  Malayan Pit Viper Calloselasma Rhodostoma Antivenom Red Cross |  Russell’s Viper Daboia Russelli Siamensis Antivenom Red Cross |
The Red Cross produces 2 kinds of polyvalent snake antivenom, one Hematotoxic Polyvalent Snake Antivenom against hematotoxic snake venom (Malayan pit viper, Green pit viper and Russell’s viper snakes) and one neurotoxic antivenom against neurotoxic snake venom (Cobra, King cobra, Banded Krait and Malayan Krait snakes).
Administration
The freeze-dried Hematotoxic Polyvalent Snake Antivenom must be reconstituted with the solution supplied (or 10 ml of sterile water for injection) prior to the administration.
Dosage of Hematotoxic Polyvalent Snake Antivenom to neutralize Malayan Pit Viper venom, Green Pit Viper venom, and Russell’s Viper venom
The initial dose of this hematotoxic polyvalent snake antivenom is 60 ml of reconstituted antivenin that should be given by slow intravenous infusion (approx. 2 ml/min). Subsequent dose can be given every 6 hours according to the clinical symptoms.
Contra-indication
None, unless the patient is known to be hypersensitive to constitutions of the product, appropriate precautions must be taken.
Side effects
Occasionally, transient tenderness at the injection site, cutaneous reaction and alterations in temperature may occur. In some cases nausea, vomiting and also circulatory reactions (e.g. tachycardia, bradycardia, hypotension, sweating, vertigo) and allergic reactions (e.g. with flush, urticaria, dyspnea) have been observed, extending in isolated cases as far as shock. Therefore, the patient should be monitored for an extended period of time.Therapeutic measures depend on the nature and severity of side effects. Antihistamines, if necessary adrenaline, high doses of corticosteroids, volume replacement, oxygen.
Special precautions
Since the Hematotoxic Polyvalent Snake Antivenom is prepared from horse serum, sensitization to heterologous protein may occur in some individuals. To avoid serious allergic reactions, skin test should be performed prior to the administration by injection of 0.02 ml of 1:100 antivenin dilution intradermally. It should be noted that the skin test may not predict the anaphylaxis nor delay serum sickness reactions.
Storage and stability
Keep in tightly closed container and store below 25-degree Celsius. The product shall have a shelf life of 5 years from the manufacturing date.
The manufacturing plant of QSMI has developed to meet the GMP requirement and get the GMP certificated from since 2003.
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