This Neuro Polyvalent Snake Antivenom can be used against Ophiophagus Hannah, Naja Kaouthia, Bungarus fasciatus venom and Bungarus candidus snakes venom.
Cobra Naja Kaouthia Antivenom Red Cross
Malayan Krait Bungarus Candidus Antivenom Red Cross
Banded Krait Bungarus fasciatus Antivenom Red Cross
The Red Cross produces 2 kinds of polyvalent snake antivenom, one hematotoxic polyvalent antivenom against hematotoxic snake venom (Malayan pit viper, Green pit viper and Russell’s viper snakes) and one Neurotoxic Polyvalent Snake Antivenom against neurotoxic snake venom (Cobra, King cobra, Banded Krait and Malayan Krait snakes).
The freeze-dried Neurotoxic Polyvalent Snake Antivenom must be reconstituted with the solution supplied (or 10 ml of sterile water for injection) prior to the administration.
Dosage of Neurotoxic Polyvalent Snake Antivenom to neutralize Cobra and King Cobra Venom, Banded Krait Venom, and Malayan Krait Venom
The initial dose of this Neurotoxic Polyvalent Snake Antivenom is 60 ml of reconstituted antivenin that should be given by slow intravenous infusion (approx. 2 ml/min). Subsequent dose can be given every 6 hours according to the clinical symptoms.
None, unless the patient is known to be hypersensitive to constitutions of the product, appropriate precautions must be taken.
Occasionally, transient tenderness at the injection site, cutaneous reaction and alterations in temperature may occur. In some cases nausea, vomiting and also circulatory reactions (e.g. tachycardia, bradycardia, hypotension, sweating, vertigo) and allergic reactions (e.g. with flush, urticaria, dyspnea) have been observed, extending in isolated cases as far as shock. Therefore, the patient should be monitored for an extended period of time.Therapeutic measures depend on the nature and severity of side effects. Antihistamines, if necessary adrenaline, high doses of corticosteroids, volume replacement, oxygen.
In cases of Cobra, King Cobra and Krait bites, respiratory support may be essential. Since Neurotoxic Polyvalent Snake Antivenom antivenin is prepared from horse serum, sensitization to heterologous protein may occur in some individuals. To avoid serious allergic reactions, skin test should be performed prior to the administration by injection of 0.02 ml of 1:100 antivenin dilution intradermally. It should be noted that the skin test may not predict the anaphylaxis nor delay serum sickness reactions.
Storage and stability
Keep in tightly closed container and store below 25-degree Celsius. The product shall have a shelf life of 5 years from the manufacturing date.
The manufacturing plant of QSMI has developed to meet the GMP requirement and get the GMP certificated from FDA since 2003.
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