Snake Antivenom for Banded Krait, Red Cross Antivenin Treatment for Bungarus fasciatus Snake
Banded Krait Antivenom to Neutralize 0.8 mg/ml of Bungarus fasciatus Snake Venom
Red cross Snake antivenom against Banded Krait snake bites for people travelling to Asia and people who own a Banded Krait snake.
Administration
The freeze-dried Banded Krait antivenom must be reconstituted with the solution supplied (or 10 ml of sterile water for injection) prior to the administration.
Dosage of Neurotoxic Banded Krait snake antivenom
Initial dose 100 ml. The reconstituted Banded Krait antivenom should be given by slow intravenous infusion (approx. 2 ml/min). Subsequent dose can be given every 12 hours according to the clinical symptoms.
Contra-indication
None, unless the patient is known to be hypersensitive to constitutions of the product, appropriate precautions must be taken.
Side effects
Occasionally, transient tenderness at the injection site, cutaneous reaction and alteration in temperature may occur. In some cases nausea, vomiting and also circulatory reactions (e.g. tachycardia, bradycardia, hypotension, sweating, vertigo) and allergic reactions (e.g. with flush, urticaria, dyspnea) have been observed, extending in isolated cases as far as shock. Therefore, the patient should be monitored for an extended period of time.Therapeutic measures depend on the nature and severity of side effects. Antihistamines, if necessary adrenaline, high doses of corticosteroids, volume replacement, oxygen.
Special precautions
Since the Banded Krait antivenom is prepared from horse serum, sensitization to heterologous protein may occur in some individuals. To avoid serious allergic reactions, skin test should be performed prior to the administration by injection of 0.02 ml of 1:100 antivenin dilution intradermally. It should be noted that the skin test may not predict the anaphylaxis nor delay serum sickness reactions.
Storage and stability
Keep in tightly closed container and store below 25-degree Celsius. The product shall have a shelf life of 5 years from the manufacturing date.
The manufacturing plant of QSMI has developed to meet the GMP requirement and get the GMP certificated from FDA since 2003.
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